Figure 4From: Protein induced by vitamin K absence or antagonist-II production is a strong predictive marker for extrahepatic metastases in early hepatocellular carcinoma: a prospective evaluation The median time to extrahepatic metastases according to the change in the serum PIVKA-II level during follow-up and extrahepatic metastases in patients with elevated levels of PIVKA-II (P < 0.001).Back to article page