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Table 2 Prostate cancer risk by subgroups

From: Serum levels of selenium and smoking habits at age 50 influence long term prostate cancer risk; a 34 year ULSAM follow-up

  Full cohort Genotyped men
  NonPrCa* PrCa PrCa-risk NonPrCa PrCa PrCa-risk
Serum selenium(μg/l) N % N % RR** 95% CI*** N % N % RR 95% CI
≤70 675 (36.7) 84 (40.4) Ref - 295 (33.6) 48 (38.1) Ref -
70.1-81.0 588 (32.0) 65 (31.2) 0.89 (0.65 - 1.24) 299 (34.0) 46 (35.7) 0.93 (0.62 - 1.4)
81+ 574 (31.2) 59 (28.4) 0.83 (0.60 - 1.16) 285 (32.4) 33 (26.2) 0.72 (0.46 - 1.12)
Erythrocyte sedimentation rate, ESR(mm/h)
≤4.0 704 (38.3) 84 (40.4) Ref - 348 (39.6) 51 (40.5) Ref -
4.1-8.0 587 (32.0) 67 (32.2) 0.97 (0.70 - 1.33) 297 (33.8) 38 (30.2) 0.89 (0.58 - 1.35)
8+ 545 (29.7) 57 (27.4) 0.88 (0.63 - 1.23) 234 (26.6) 37 (29.4) 1.07 (0.7 - 1.62)
Total serum cholesterol(mmol/l)
≤6.24 560 (30.5) 76 (36.5) Ref - 288 (32.8) 48 (38.1) Ref -
6.25-7.27 624 (34.0) 64 (30.8) 0.77 (0.55 - 1.07) 295 (33.6) 40 (31.7) 0.82 (0.54 - 1.25)
7.27+ 653 (35.5) 68 (32.7) 0.78 (0.56 - 1.08) 296 (33.7) 38 (30.2) 0.78 (0.51- 1.19)
BMI(kg/m 2 )
≤23.4 605 (32.9) 61 (29.3) Ref - 296 (33.7) 39 (31.0) Ref -
23.5-26.0 567 (30.9) 78 (37.5) 1.34 (0.96 - 1.87) 285 (32.4) 50 (39.7) 1.31 (0.86 - 1.99)
26+ 665 (36.2) 69 (33.2) 1.03 (0.73 - 1.46) 298 (33.9) 37 (29.4) 0.96 (0.61 - 1.5)
Smoking
non-smoker 449 (24.4) 69 (33.2) Ref - 258 (29.4) 45 (35.7) Ref -
smoker 961 (52.3) 86 (41.3) 0.6 (0.44 - 0.83) 394 (44.8) 47 (37.3) 0.70 (0.46 - 1.05)
ex-smoker 427 (23.2) 53 (25.5) 0.82 (0.58 - 1.18) 227 (25.8) 34 (27.0) 0.87 (0.56 - 1.36)
  1. Unadjusted relative risk (RR) of prostate cancer (PrCa) for baseline tertiles of selenium with 95% confidence intervals (CI), the two selenium level modifying factors ESR, total cholesterol, BMI and for smoking status in the full cohort and in the genotyped men. The lowest tertiles and the non-smokers were used as references.
  2. * Prostate cancer
  3. ** Relative risk
  4. *** Confidence interval