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Table 6 Variables associated with overall surviva l in multivariate regression analyses: PMHI vs. RMI

From: Early mortality and overall survival in oncology phase I trial participants: can we improve patient selection?

Overall Survival Predictors

Hazard Ratio

95% CI

p-value

PMHI

   Albumin < 35 g/L

1.99

0.86-4.58

0.11

   > 2 metastatic sites

1.79

1.26-2.53

0.01

   ECOG Performance Status > 0

1.36

0.96-1.91

0.08

RMI

   Albumin < 35 g/L

1.94

0.84-4.48

0.12

   > 2 metastatic sites

1.74

1.23-2.48

0.01

   LDH > ULN

1.69

1.20-2.38

0.01

  1. Abbreviations: PMHI = Princess Margaret Hospital Index; RMI = Royal Marsden Hospital Index; ECOG = Eastern Cooperative Oncology Group; LDH = lactate dehydrogenase; ULN = upper limit of normal; CI = confidence interval
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BMC Cancer

ISSN: 1471-2407

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