Skip to main content

Table 3 Associations between the mRNA expression of CD44 isoforms and the cancer stem cell phenotypes CD44+/CD24- and ALDH1+ (as determined by IHC).

From: CD44 isoforms are heterogeneously expressed in breast cancer and correlate with tumor subtypes and cancer stem cell markers

Splice variant

CD44+/CD24-

ALDH1+

 

All2

n = 80

Negative2

n = 51 (64%)

Positive2

n = 29 (36%)

P1

All2

n = 73

Neg/Weak2

n = 61(84%)

Strong2

n = 12 (16%)

P1

CD44v2-v10

1.650

1.580

1.843

0.045

1.594

1.594

1.706

0.69

CD44v3-v10

1.231

1.124

1.380

0.002

1.188

1.224

1.131

0.92

CD44v8-v10

1.440

1.115

1.640

0.0007

1.457

1.457

1.387

0.81

CD44S

0.257

0.293

0.214

0.024

0.261

0.240

0.467

0.011

CD44 total

0.702

0.628

0.818

0.002

0.699

0.629

0.763

0.24

  1. 1 Mann-Whitney test
  2. 2 Median values