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Table 2 Correlations of the mRNA expression of different CD44 splice variants to total CD44 mRNA and protein expression as determined by q-RT-PCR and IHC respectively.

From: CD44 isoforms are heterogeneously expressed in breast cancer and correlate with tumor subtypes and cancer stem cell markers

Splice variant

CD44 total mRNA expression

(n = 187)

CD44 protein expression

(n = 80)

 

ρ1

P-value

ρ1

P-value

CD44v2-v10

0.58

< 0.00001

0.25

0.026

CD44v3-v10

0.72

< 0.00001

0.34

0.002

CD44v8-v10

0.64

< 0.00001

0.36

0.001

CD44S

0.26

0.001

-0.20

0.070

CD44 total

-

-

0.37

0.001

  1. 1Spearman's correlation coefficient (rho)