Figure 4
Expression of alternatively spliced transcripts of CD44 in breast cancer tumors classified into molecular subtypes. A-E. All isoforms except for the CD44 standard were differentially expressed in the different molecular subtypes. The CD44v2-v10 and CD44v3-v10 variants were highly expressed in luminal A tumors whereas the CD44v8-v10 isoform was associated to basal- and normal-like tumors. The CD44 standard variant had the highest median expression in HER2-enriched tumors. The numbers of tumors in each subtype are shown at top.