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Table 2 Effects of MK-0457 on TT cell ploidy.

From: Aurora kinases are expressed in medullary thyroid carcinoma (MTC) and their inhibition suppresses in vitro growth and tumorigenicity of the MTC derived cell line TT

Cell cycle phase Control MK-0457 t-test
Sub G0/G1 0.53 ± 0.13 0.33 ± 0.12 p = 0.12
Go/G1 51.35 ± 4.84 3.32 ± 0.09 p < 0.01
S 4.94 ± 0.94 0.72 ± 0.02 p < 0.01
G2/M 15.03 ± 0.05 22.37 ± 2.84 p < 0.05
Polyploid 16.57 ± 3.25 60.59 ± 2.66 p < 0.01