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Table 2 Effects of MK-0457 on TT cell ploidy.

From: Aurora kinases are expressed in medullary thyroid carcinoma (MTC) and their inhibition suppresses in vitro growth and tumorigenicity of the MTC derived cell line TT

Cell cycle phase

Control

MK-0457

t-test

Sub G0/G1

0.53 ± 0.13

0.33 ± 0.12

p = 0.12

Go/G1

51.35 ± 4.84

3.32 ± 0.09

p < 0.01

S

4.94 ± 0.94

0.72 ± 0.02

p < 0.01

G2/M

15.03 ± 0.05

22.37 ± 2.84

p < 0.05

Polyploid

16.57 ± 3.25

60.59 ± 2.66

p < 0.01

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BMC Cancer

ISSN: 1471-2407

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