Correlation of Aurora kinases expression with the TNM stage and RET status. (A) The Aurora kinase mRNAs level in MTC tissues was quantified as described in the Materials and Methods section. The statistical analysis of differences in the expression level of the three kinases in MTC tissues at different TNM stages was assessed by the analysis of variance (ANOVA) followed by the Tukey post ANOVA test. (B) Aurora kinases mRNA level in MTC tissues harboring the wild type (WT) or the mutated (Mut) RET protein. The bars in the graphs indicate the median values.