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Table 3 Multivariate analysis of clinical and biochemical factors

From: Prognostic and predictive value of clinical and biochemical factors in breast cancer patients with bone metastases receiving "metronomic" zoledronic acid

Clinical and biochemical factor

category

HR (95% CI)

P

Previous chemotherapy regimen

≤ 2

1

0.000

 

> 2

7.803 (2.884-21.112)

 

ER status

-

1

0.001

 

+

0.295 (0.141-0.618)

 

Baseline NTx

≤ 18 nM BCE

1

0.001

 

> 18 nM BCE

2.842 (1.458-5.539)

 

VEGF (days 90)

≤ 500 pg/ml

1

0.020

 

> 500 pg/ml

2.220 (1.136-4.338)

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