| | |
Metronomic arm
|
Conventional arm
|
P
|
|---|
| | |
No
|
%
|
No
|
%
| |
|---|
|
Median age (range)
| |
46 (35-73)
|
51 (33-73)
|
0.1040
|
|
ER status
|
+
|
22
|
73.3
|
18
|
60.0
|
0.3950
|
| |
-
|
7
|
23.3
|
11
|
36.6
| |
|
Her-2 status
|
+
|
3
|
10.0
|
4
|
13.3
|
1.0000
|
| |
-
|
22
|
73.3
|
24
|
80.0
| |
|
Primary tumor
|
T1, T2
|
26
|
86.7
|
30
|
100.0
|
0.1120
|
| |
T3, T4
|
4
|
13.3
|
0
|
0
| |
|
Disease free interval*
|
>2 years
|
23
|
76.7
|
20
|
66.7
|
0.5670
|
| |
≤ 2 years
|
7
|
23.3
|
10
|
33.3
| |
|
Lymph node
|
0 ≤ N ≤ 3
|
25
|
83.3
|
22
|
73.3
|
0.5320
|
| |
N>3
|
5
|
16.7
|
8
|
26.7
| |
|
Previous radiotherapy
|
yes
|
18
|
60.0
|
20
|
66.7
|
0.7890
|
| |
no
|
12
|
40.0
|
10
|
33.3
| |
|
Primary histology
|
IDC
|
29
|
96.7
|
28
|
93.3
|
1.0000
|
| |
ILC
|
1
|
3.3
|
2
|
6.7
| |
|
Grade
|
1
|
9
|
30.0
|
6
|
20.0
|
0.7180
|
| |
2
|
14
|
46.7
|
16
|
53.3
| |
| |
3
|
4
|
13.3
|
3
|
10.0
| |
|
Menopausal
|
pre
|
17
|
56.7
|
14
|
46.7
|
0.6060
|
| |
post
|
13
|
43.3
|
16
|
53.3
| |
|
Previous chemotherapy regimen
|
≤ 2
|
26
|
86.7
|
22
|
73.3
|
0.3330
|
| |
>2
|
4
|
13.3
|
8
|
26.7
| |
|
Bone metastasis sites
|
1
|
11
|
36.7
|
9
|
30.0
|
0.7850
|
| |
≥ 2
|
19
|
63.3
|
21
|
70.0
| |
- * Disease free interval = date from surgery to first recurrence
