Table 1 Patient characteristics
| Â | Â | Metronomic arm | Conventional arm | P | ||
|---|---|---|---|---|---|---|
| Â | Â | No | % | No | % | Â |
Median age (range) | Â | 46 (35-73) | 51 (33-73) | 0.1040 | ||
ER status | + | 22 | 73.3 | 18 | 60.0 | 0.3950 |
| Â | - | 7 | 23.3 | 11 | 36.6 | Â |
Her-2 status | + | 3 | 10.0 | 4 | 13.3 | 1.0000 |
| Â | - | 22 | 73.3 | 24 | 80.0 | Â |
Primary tumor | T1, T2 | 26 | 86.7 | 30 | 100.0 | 0.1120 |
| Â | T3, T4 | 4 | 13.3 | 0 | 0 | Â |
Disease free interval* | >2 years | 23 | 76.7 | 20 | 66.7 | 0.5670 |
|  | ≤ 2 years | 7 | 23.3 | 10 | 33.3 |  |
Lymph node | 0 ≤ N ≤ 3 | 25 | 83.3 | 22 | 73.3 | 0.5320 |
| Â | N>3 | 5 | 16.7 | 8 | 26.7 | Â |
Previous radiotherapy | yes | 18 | 60.0 | 20 | 66.7 | 0.7890 |
| Â | no | 12 | 40.0 | 10 | 33.3 | Â |
Primary histology | IDC | 29 | 96.7 | 28 | 93.3 | 1.0000 |
| Â | ILC | 1 | 3.3 | 2 | 6.7 | Â |
Grade | 1 | 9 | 30.0 | 6 | 20.0 | 0.7180 |
| Â | 2 | 14 | 46.7 | 16 | 53.3 | Â |
| Â | 3 | 4 | 13.3 | 3 | 10.0 | Â |
Menopausal | pre | 17 | 56.7 | 14 | 46.7 | 0.6060 |
| Â | post | 13 | 43.3 | 16 | 53.3 | Â |
Previous chemotherapy regimen | ≤ 2 | 26 | 86.7 | 22 | 73.3 | 0.3330 |
| Â | >2 | 4 | 13.3 | 8 | 26.7 | Â |
Bone metastasis sites | 1 | 11 | 36.7 | 9 | 30.0 | 0.7850 |
|  | ≥ 2 | 19 | 63.3 | 21 | 70.0 |  |