Figure 4
From: Cytoplasmic p21 is a potential predictor for cisplatin sensitivity in ovarian cancer
Inhibition of p21 translocation into cytoplasm enhances the sensitivity to cisplatin in C13*, while induction of p21 translocation into the cytoplasm results in increased resistance to cisplatin in OV2008. (A) Representative western blot images showing the changes in Akt, p-Akt and cytoplasmic p21 in C13*. (B) Representative western blot images showing the changes in Akt, p-Akt and cytoplasmic p21 in OV2008. (C) Apoptosis rates of C13* cells in response to cisplatin. (D) Apoptosis rates of OV2008 cells in response to cisplatin. (*, p < 0.05).