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Table 1 Proposed (1998 draft) ICD-10 Criteria for Cancer-Related Fatigue

From: An examination of cancer-related fatigue through proposed diagnostic criteria in a sample of cancer patients in Taiwan

Six (or more) of the following symptoms have been present every day or nearly every day during the same 2-week period in the past month, and at least one of the symptoms is (A1) significant fatigue.

A1. Significant fatigue, diminished energy, or increased need to

rest, disproportionate to any recent change in activity level

A2. Complaints of generalized weakness or limb heaviness

A3. Diminished concentration or attention

A4. Decreased motivation or interest to engage in usual activities

A5. Insomnia or hypersomnia

A6. Experience of sleep as unrefreshing or nonrestorative

A7. Perceived need to struggle to overcome inactivity

A8. Marked emotional reactivity (eg, sadness, frustration,

or irritability) to feeling fatigued

A9. Difficulty completing daily tasks attributed to feeling fatigued

A10. Perceived problems with short-term memory

A11. Postexertional malaise lasting several hours

B. The symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning

C. There is evidence from the history, physical examination, or laboratory

findings that the symptoms are a consequence of cancer or cancer therapy.

D. The symptoms are not primarily a consequence of comorbid psychiatric

disorders such as major depression, somatization disorder, somatoform disorder, or delirium.