Kaplan-Meier curves showing disease-specific mortality of UM patients. Patients are grouped according to the EFS methylation status in their tumor. Partially and fully methylated samples are grouped together (A, B and C). (A) Set I: 16 patients used for the initial EFS CGI methylation analysis (p = 0.02). (B) Set II; confirmatory cohort of 24 randomly chosen tumor samples (p = 0.02). (C) Combined analysis of all 40 samples (setI + set II). (D) Combined analysis of all 40 samples (setI + set II) with partially methylated samples as separate group.