Figure 2From: FLT3 mutations in canine acute lymphocytic leukemia FLT3 ITD mutations in exon 14. The amino acid sequences of the three FLT3 ITD mutations are shown, with the duplicated region shown below the wild-type sequence of exon 14 for each case. The bolded amino acid(s) are not part of the wild-type sequence and exist between the two repeats (not duplicated). The underlined residue in Case 2 is mutated in the duplication only; the other copy is wild-type. Each of the three ITD mutations are in-frame.Back to article page