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Table 2 Comparing Groups: End of study tumor summary

From: A moderate elevation of circulating levels of IGF-I does not alter ErbB2 induced mammary tumorigenesis

  ErbB2 Bigenic IGF-I Wild Type
Number of Tumors 19(20) = 95% 19(21) = 90% 0(25) 0(22)
Mean Time to Tumor Formation (MTTF) 224 days 30 wks/7.5 m 233 days 33 wks/8.3 m NA NA
Average Number of Tumors per Animal 2.2 (11) = 55% 2.3 (13) = 60% NA NA
  1. Number of tumors = animals that got mammary tumors (total number of animals) %- percentage of animals with mammary tumors per group; Average number of tumors per animal = average number of mammary gland tumors per animal (number of animals with multiple tumors), %- percentage of animals with multiple tumors per group. NA = not applicable. ErbB2 = MMTV-ErbB2 transgenic; Bigenic = TTR-IGF-I-ErbB2 bigenic; IGF-I = TTR-IGF-I transgenic; Wild Type = control; wks = weeks; m = months.