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Figure 7 | BMC Cancer

Figure 7

From: Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis

Figure 7

Analysis of integrin gene expression. PC-3 or LNCaP cells were treated with 1 μM AEE788, 1 mM VPA or 1 nM RAD001, or with all compounds simultaneously (triple). Non-treated cells served as the controls. Primer sets used for evaluation are listed in materials and methods. Calculation of the relative expression of each gene was done by the ΔΔCt method in the analysis program of SABioscience Corporation. The housekeeping gene GAPDH was used for normalisation. One representative from three separate experiments is shown. *indicates significant difference to controls, #indicates significant difference to single drug treatment.

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BMC Cancer

ISSN: 1471-2407

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