Antioxidants and breast cancer risk- a population-based case-control study in Canada

Pan, Sai Yi; Zhou, Jia; Gibbons, Laurie; Morrison, Howard; Wen, Shi Wu

doi:10.1186/1471-2407-11-372

BMC Cancer

Table 5 ORs of breast cancer associated with total intake of antioxidants, NECSS,Canada,1994-1997

From: Antioxidants and breast cancer risk- a population-based case-control study in Canada

	Premenopausal				Postmenopausal
Variable	Cases	Controls	OR † (95% CI)	p	Cases	Controls	OR†† (95% CI)	p
Beta-carotene
From Diet only
Low or no intake	423	435	1.00		781	837	1.00
High intake *	443	410	1.09 (0.88-1.34)	0.43	715	780	0.96 (0.82-1.13)	0.66
From supplementation only
Low or no intake	864	836	1.00		1487	1598	1.00
High intake**	2	9	0.11 (0.01-0.88)	0.04	9	19	0.47 (0.20-1.08)	0.07
From both sources
Low or no intake	856	833	1.00		1473	1589	1.00
High intake***	10	12	0.77 (0.32-1.87)	0.57	23	28	0.69 (0.37-1.27)	0.23
Vitamin C (years)
From Diet only
Low or no intake	467	489	1.00		861	962	1.00
High intake *	399	356	1.23 (0.99-1.53)	0.06	635	655	1.24 (0.99-1.42)	0.07
From supplementation only
Low or no intake	823	794	1.00		1405	1524	1.00
High intake**	43	51	0.70 (0.44-1.10)	0.12	91	93	0.85 (0.61-1.17)	0.32
From both sources
Low or no intake	812	779	1.00		1352	1463	1.00
High intake***	54	66	0.65 (0.44-0.98)	0.04	144	154	0.78 (0.60-1.03)	0.08
Vitamin E (years)
From Diet only
Low or no intake	451	454	1.00		837	922	1.00
High intake *	415	391	0.98 (0.78-1.22)	0.85	659	695	1.06 (0.89-1.25)	0.53
From supplementation only
Low or no intake	852	828	1.00		1451	1555	1.00
High intake**	14	17	0.72 (0.33-1.59)	0.42	45	62	0.64 (0.42-0.99)	0.04
From both sources
Low or no intake	841	814	1.00		1392	1503	1.00
High intake***	25	31	0.71 (0.40-1.25)	0.23	104	114	0.86 (0.64-1.17)	0.35
Zinc (years)
From Diet only
Low or no intake	430	451	1.00		747	855	1.00
High intake *	436	394	1.13 (0.89-1.45)	0.32	749	762	1.13 (0.94-1.35)	0.20
From supplementation only
Low or no intake	859	830	1.00		1487	1597	1.00
High intake**	7	15	0.29 (0.10-0.83)	0.02	9	20	0.41 (0.18-0.96)	0.04
From both sources
Low or no intake	855	831	1.00		1478	1590	1.00
High intake***	11	14	0.73 (0.31-1.72)	0.47	18	27	0.51 (0.27-0.97)	0.04
Selenium (years)
From Diet only
Low or no intake	417	426	1.00		747	822	1.00
High intake *	449	419	1.01 (0.79-1.29)	0.93	749	795	0.99 (0.82-1.18)	0.88
From supplementation only
Low or no intake	861	834	1.00		1488	1604	1.00
High intake**	5	11	0.39 (0.13-1.16)	0.09	8	13	0.50 (0.19-1.32)	0.16
From both sources
Low or no intake	861	842	1.00		1480	1603	1.00
High intake***	5	3	1.77 (0.33-9.69)	0.51	16	14	0.82 (0.37-1.80)	0.61

† Adjusted for age, province of residence, education, smoking pack years, alcohol consumption, number of live births, age at menarche, and total energy intake.
†† Adjusted for age, province of residence, education, smoking pack years, alcohol consumption, BMI, recreational physical activity, number of live births, age at menarche, and total energy intake.
* In comparison with low intake (lower than median intake).
** In comparison with low intake (less than 10 years of supplementation).
*** In comparison with not high intake from both sources.

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ISSN: 1471-2407

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