|
Institute
|
Treatment (percentage of using chemotherapy)
|
Fistula formation/or skin dehiscence
|
*≥ Grade 3
|
|---|
| | | |
dermatitis
|
mucosistis
|
Body weight loss
|
^Xerostomia (acute)
|
Anemia
|
Leukopenia
|
Thrombocytopenia
|
|---|
|
RTOG 9501[4]
|
OP+RT+C/T
|
-
|
8%
|
30%
|
-
|
2%
| |
38% (all of hematologic effects)
| |
|
EORTC 22931[5]
|
OP+RT+C/T
|
-
|
-
|
41%
|
-
|
14%
|
-
|
16%
|
-
|
|
RTOG 0024[14]
|
OP+RT+C/T
|
11%
|
29%
|
60%
|
-
|
-
| |
12% (all of hematologic effects)
| |
|
Yu et al.[23]
|
OP+RT
|
8-29%
|
-
|
-
|
-
|
-
|
-
|
-
|
-
|
|
Jeremic et al.[24]
|
RT+C/T
|
-
|
-
|
-
|
29%
|
-
|
-
|
-
|
-
|
|
Capuano et al.[25]
|
RT+C/T
|
-
|
-
|
-
|
17%
|
-
|
-
|
-
|
-
|
|
Gomez et al.[19]
|
OP+IMRT +C/T (29%)
|
-
|
3%
|
23%
|
-
|
0%
|
-
|
-
|
-
|
|
Chen WC et al. Taiwan [17]
|
OP+IMRT +C/T (9%)
|
-
|
0
|
14%
|
-
|
-
|
-
|
-
|
-
|
|
FEMH, Taiwan
|
OP+HT +C/T (84%)
|
11%
|
5%
|
42%
|
`0%
|
`0%
|
0%
|
5%
|
0%
|
- ^Toxicity of xelostomia (Acute): Acute toxicities is defined as occurring < 90 days after beginning RT.
- *The grade of toxicity is according to the Common Terminology Criteria for Adverse Events v3.0 (CTCAE v3.0).
-
Abbreviations:
- OP = operation; RT = External beam radiation therapy; IMRT = intensity-modulated radiation therapy; HT = helical tomotherapy; C/T chemotherapy; FEMH = Far Eastern Memorial Hospital.
