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Table 3 Medical decision making on neoadjuvant treatment

From: Clinical management of gastric cancer: results of a multicentre survey

Neoadjuvant practice

Recommendation of the Guidelines

Oncological surgeons

Medical oncologists

Radiation oncologists

p

  

N

%

N

%

N

%

 

adenocarcinoma cT4N0M0

gastrectomy or preoperative chemotherapy

      

0.612

gastrectomy

 

40

39.60

75

46.58

27

28.13

 

preoperative chemotherapy

 

48

47.52

72

44.72

41

42.71

 

preoperative radiotherapy

 

0

0

0

0

0

0

 

preoperative chemoradiation

 

13

12.87

14

8.70

28

29.17

 

adenocarcinoma cT2N2M0

gastrectomy or preoperative chemotherapy

      

0.040

gastrectomy

 

70

69.31

77

47.83

30

31.25

 

preoperative chemotherapy

 

18

17.82

73

45.34

38

39.58

 

preoperative radiotherapy

 

0

0

0

0

0

0

 

preoperative chemoradiation

 

13

12.87

11

6.83

28

29.17

 

regimen usually used in neoadjuvant setting

ECF(EPI+DDP+5FU)

      

0.634

CF(DDP+5FU)

 

21

20.79

29

18.01

15

15.63

 

ECF(EPI+DDP+5FU)

 

15

14.85

35

21.74

14

14.58

 

fluoropyrimidine(5Fu or Capecitabine)

 

24

23.76

7

4.35

7

7.30

 

oxaliplatin based regimen

 

23

22.77

63

39.13

35

36.46

 

irinotecan based regimen

 

12

11.88

5

3.11

9

9.38

 

paclitaxel or docetaxel based regimen

 

6

5.94

22

13.66

16

16.67

 

combination of above or other

 

0

0

0

0

0

0

 

how long neoadjuvant chemotherapy last

3 cycles, about 2 months

      

0.213

< 1 m

 

21

20.79

19

11.80

8

8.33

 

1-3 m

 

76

75.25

127

78.88

79

82.29

 

> 3 m

 

4

3.96

15

9.32

9

9.38

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