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Table 1 List of proteins that displayed significantly reduced expression levels in PNP-GDEPT treated samples

From: Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: A tangible union against chemoresistant cancer

Name of the Protein
Identified
Hit Value
(untreated/treated)
Ratio
Transformed log
(untreated:treated)1
Keratin 5 13/0 19,306
Keratin 77 12/0 18,502
Cadherin 6 (K-cadherin) 7/0 14,999
Desmoplakin 6/0 14,037
Plakoglobin 3/0 10,000
Spondin 1 3/0 10,000
Dynactin 1 2/0 7,925
Agrin 2/0 7,925
Filaggrin 2/0 7,925
Karyopherin alpha1 2/0 7,925
Antiquitin (ALDH7A1) 2/0 7,925
Epoxide hydrolase 2/0 7,925
Insulysin 2/0 7,925
BRI3 binding protein
(Cervical cancer 1 proto-oncogene-binding protein KG19)
3/0 10,000
Ribosomal protein L4 5/0 12,924
Eukaryotic translation initiation factor 3 subunit 2 (eIF-3 beta) 3/0 10,000
Mitochondrial trifunctional protein, beta subunit 3/0 10,000
Polymerase (RNA) II (DNA directed) polypeptide E 3/0 10,000
Dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 5/0 12,924
v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) (RalB) 2/0 7,925
  1. 1 Confidence intervals for estimated mean of population: For 0.95 CI: 232.9632 ± 123.8158; For 0.99 CI: 232.9632 ± 163.636