Figure 3
From: The BH3 mimetic ABT-737 increases treatment efficiency of paclitaxel against hepatoblastoma
Immunhistological analysis of HB tumours. Images show staining of Haematoxilin and Eosin (A-D), detection of Ki-67 (E-H) and Tunel assay (I-L). For each representative samples of controls (A, E, I), paclitaxel (B, F, J), ABT-737 (C, G, K) and combination (D, H, L) are provided. Combined treatment using paclitaxel and ABT-737 reveals high tissue damage and a low proliferation index. Multiple picnotic nuclei denote necrotic tissue destruction. Brown staining shows Ki-67 positive cells. Bright green fluorescences are apoptotic cells. Nuclear staining was done by Hematoxylin and DAPI, respectively.