Table 3 Changes in kinetic parameters and tumor size in 24 patients after systemic neoadjuvant chemotherapy
Patient # | Ktrans changes | Ve changes | Size changes | Clinical | Final pathologic finding | ||
|---|---|---|---|---|---|---|---|
| Â | AIF theoretical | AIF measured | AIF theoretical | AIF measured | N/A | Response | Sataloff Grade |
1 | -70% | -23% | -73% | -80% | 0% | PR | C |
2 | -35% | -20% | -4% | -52% | 57% | SD | C |
3 | -2% | 108% | -89% | -91% | -100% | PR | C |
4 | -71% | -22% | -46% | -48% | -84% | SD | C |
5 | 223% | 166% | -76% | -74% | -100% | PR | C |
6 | -97% | -84% | 23% | -29% | 158% | PR | C |
7 | -85% | -67% | -78% | -64% | -72% | PR | C |
8 | -93% | 93% | -15% | -52% | -99% | CR | C |
9 | -98% | -98% | -50% | -38% | -65% | PR | D |
10 | -90% | -82% | -50% | -59% | -100% | PR | C |
11 | -97% | -89% | -49% | 193% | -62% | PR | C |
Median (C+D) | -85% | -23% | -50% | -52% | -72% | Â | Â |
95 CI | [-110%,17%] | [-72%,51%] | [-69%,-23%] | [-88%,17%] | [-98%,13%] | Â | Â |
12 | -85% | -95% | -61% | -73% | -71% | CR | B |
13 | -99% | -86% | -65% | -77% | -73% | PR | B |
14 | -54% | -89% | -57% | -48% | -100% | SD | B |
15 | -94% | -95% | -75% | -75% | -33% | SD | B |
16 | 65% | -52% | -68% | -72% | -100% | PR | B |
17 | -96% | -84% | -72% | -85% | -91% | PR | B |
18 | -97% | -97% | -77% | -91% | -29% | PR | B |
Median (B) | -94% | -89% | -68% | -75% | -73% | Â | Â |
95 CI | [-121%,-10%] | [-100%,-71%] | [-75%,-61%] | [-87%,-62%] | [-98%,-44%] | Â | Â |
Median (B+C+D) | -88% | -83% | -63% | -68% | -73% | Â | Â |
95 CI | [-95%,-14%] | [-80%,0%] | [-69%,-40%] | [-82%,-19%] | [-87%,-20%] | Â | Â |
19 | 0% | 27% | -89% | -89% | -40% | PR | A |
20 | -15% | -91% | -62% | -95% | -99% | CR | A |
21 | 4% | -54% | -89% | -91% | -100% | CR | A |
22 | -29% | -98% | -51% | -73% | -100% | CR | A |
23 | -99% | -100% | -95% | -94% | -96% | CR | A |
24 | -94% | -99% | -75% | -87% | -97% | PR | A |
Median (A) | -22% | -94% | -82% | -90% | -98% | Â | Â |
95 CI | [-87%,10%] | [-122%,-16%] | [-95%,-59%] | [-97%,-80%] | [-114%,-64%] | Â | Â |