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Table 3 Changes in kinetic parameters and tumor size in 24 patients after systemic neoadjuvant chemotherapy

From: Accuracy of perfusion MRI with high spatial but low temporal resolution to assess invasive breast cancer response to neoadjuvant chemotherapy: a retrospective study

Patient # Ktrans changes Ve changes Size changes Clinical Final pathologic finding
  AIF theoretical AIF measured AIF theoretical AIF measured N/A Response Sataloff Grade
1 -70% -23% -73% -80% 0% PR C
2 -35% -20% -4% -52% 57% SD C
3 -2% 108% -89% -91% -100% PR C
4 -71% -22% -46% -48% -84% SD C
5 223% 166% -76% -74% -100% PR C
6 -97% -84% 23% -29% 158% PR C
7 -85% -67% -78% -64% -72% PR C
8 -93% 93% -15% -52% -99% CR C
9 -98% -98% -50% -38% -65% PR D
10 -90% -82% -50% -59% -100% PR C
11 -97% -89% -49% 193% -62% PR C
Median (C+D) -85% -23% -50% -52% -72%   
95 CI [-110%,17%] [-72%,51%] [-69%,-23%] [-88%,17%] [-98%,13%]   
12 -85% -95% -61% -73% -71% CR B
13 -99% -86% -65% -77% -73% PR B
14 -54% -89% -57% -48% -100% SD B
15 -94% -95% -75% -75% -33% SD B
16 65% -52% -68% -72% -100% PR B
17 -96% -84% -72% -85% -91% PR B
18 -97% -97% -77% -91% -29% PR B
Median (B) -94% -89% -68% -75% -73%   
95 CI [-121%,-10%] [-100%,-71%] [-75%,-61%] [-87%,-62%] [-98%,-44%]   
Median (B+C+D) -88% -83% -63% -68% -73%   
95 CI [-95%,-14%] [-80%,0%] [-69%,-40%] [-82%,-19%] [-87%,-20%]   
19 0% 27% -89% -89% -40% PR A
20 -15% -91% -62% -95% -99% CR A
21 4% -54% -89% -91% -100% CR A
22 -29% -98% -51% -73% -100% CR A
23 -99% -100% -95% -94% -96% CR A
24 -94% -99% -75% -87% -97% PR A
Median (A) -22% -94% -82% -90% -98%   
95 CI [-87%,10%] [-122%,-16%] [-95%,-59%] [-97%,-80%] [-114%,-64%]   
  1. Final pathologic findings were graded according to the scale established by Sataloff: complete responder group (grade A), partial responder group (grade B), responder group (A+B), and non-responder group (grade C+ D). Surgery performed after neoadjuvant chemotherapy included mastectomy or conservative treatment or inadequate conservative surgery followed by mastectomy. SD = stable disease, PR = partial responder, CR = complete responder.