Images show changes in transfer constant (K
) in patient 22, complete responder to neoadjuvant chemotherapy (Sataloff A). Columns show in A and D: anatomic subtraction images; in B and E: corresponding Ktrans map acquired using measured Arterial Input Function (AIF); and in C and F: corresponding Ktrans map acquired using theoretical AIF. Images A, B, and C show data before neoadjuvant chemotherapy treatment and images D, F, and G are post-treatment. After treatment a decrease of -98% is seen in Ktrans using measured AIF values and a decrease of -29% using theoretical AIF values. Note the difference between Ktrans values before treatment when using measured and theoretical AIFs. To increase visibility of the color encoded Ktrans pixels the scale was reduced in postchemotherapy images.