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Table 3 Distribution of QoL scores by stage of disease and prior treatment history

From: Quality of life assessment as a predictor of survival in non-small cell lung cancer

QLQ-C30 Scale Stage of disease Treatment History
  Locoregional
(N = 511)
Metastatic
(N = 656)
P Newly diagnosed
(N = 605)
Previously treated
(N = 589)
P
Global 53.8 53.1 0.63 56.1 50.8 0.001
Physical 69.4 68.0 0.35 73.1 64.1 < 0.001
Role 60.4 57.2 0.12 62.4 55.2 < 0.001
Emotional 64.5 63.5 0.55 63.3 64.8 0.33
Cognitive 75.1 74.5 0.68 75.9 73.7 0.16
Social 62.0 60.2 0.35 65.3 56.8 < 0.001
Fatigue 45.0 48.6 0.03 43.1 50.6 < 0.001
Nausea/Vomiting 13.9 15.1 0.36 12.2 16.8 < 0.001
Pain 34.7 39.0 0.02 34.0 40.3 0.001
Dyspnea 39.5 36.0 0.08 34.7 40.6 0.002
Insomnia 39.0 41.0 0.31 40.5 39.3 0.54
Appetite Loss 30.2 32.3 0.29 28.4 34.1 0.004
Constipation 22.7 25.4 0.14 23.2 25.2 0.27
Diarrhea 9.9 9.8 0.92 8.8 10.9 0.07
  1. Higher scores in the global and functioning scales and lower scores in the symptom scales indicate better QoL.