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Table 3 Summary of statistical analysis for 200 and 1000 cancer cells after evaluation for Ki-67 proliferation

From: Ki67 proliferation in core biopsies versus surgical samples - a model for neo-adjuvant breast cancer studies

Statistical test 200 cells 1000 cells
  Mean difference
(95% CI)
p Mean
difference
(95% CI)
p
t-test,
linear scale
3.9% *
0.1% - 7.8%
0.046 2.2%*
-1.1% - 5.6%
0.19
t-test, linear scale
excluding outlier
4.8% *
1.2% - 8.3%
0.009 3.1%*
0.03% - 6.0%
0.03
t-test multiplicative scale 0.81 **
0.65-1.01
0.063 0.85 **
0.67-1.08
0.18
Wilcoxon***   0.03   0.06
  Disparate pairs
(distribution)
p Disparate pairs
(distribution)
p
Dichotomy
McNemar's test
12
(10+2)****
0.04 8
(4+4)****
1.0
  1. *Core biopsies' average proliferation is higher than surgical samples'
  2. ** Geometric mean of the ratios (surgical specimens/core biopsies)
  3. *** Wilcoxon matched-pairs signed-ranks test
  4. ****Instance of core biopsies as more proliferative + instances of surgical samples as more proliferative