Table 1 SNPs genotyped in EPICOLON from the previously identified category and the mucin gene family to evaluate their implication in CRC genetic susceptibility.
Gene | SNP ID | Chr | Position* | Category | SNP type | Alleles |
|---|---|---|---|---|---|---|
MTHFR | rs1801133 | 1 | 11856378 | Previously identified | Missense (A222V) | C/T |
IRS1 | rs1801278 | 2 | 227660544 | Previously identified | Missense (G971R) | A/G |
PPARG | rs1801282 | 3 | 12393125 | Previously identified | Missense (P12A) | C/G |
IL8 | rs4073 | 4 | 74606024 | Previously identified | Promoter | A/T |
ADH1C | rs698 | 4 | 100260789 | Previously identified | Missense (I350V) | A/G |
APC | rs459552 | 5 | 112176756 | Previously identified | Missense (V1822D) | A/T |
IL6 | rs1800795 | 7 | 22766645 | Previously identified | Promoter | C/G |
CCDN1 | rs9344 | 11 | 69462910 | Previously identified | Synonymous (P241P) | A/G |
VDR | rs2228570 | 12 | 48272895 | Previously identified | Missense (M1T) | C/T |
ARL11 | rs3803185 | 13 | 50205025 | Previously identified | Missense (C158R) | A/G |
OVGP1 | rs10067 | 1 | 111957311 | Mucin family | Missense (H604Q) | C/G |
GALNT14 | rs2288101 | 2 | 31135184 | Mucin family | Missense (Q469K) | A/C |
GALNT14 | rs11676188 | 2 | 31352788 | Mucin family | Intronic | C/G |
GALNTL2 | rs2102302 | 3 | 16215650 | Mucin family | Promoter | A/G |
MUC13 | rs12732 | 3 | 124624568 | Mucin family | 3'-UTR | C/T |
MUC13 | rs4679392 | 3 | 124646594 | Mucin family | Missense (I99T) | A/G |
MUC7 | rs6826961 | 4 | 71346701 | Mucin family | Missense (N80K) | C/G |
GALNT10 | rs6580076 | 5 | 153783753 | Mucin family | Synonymous (A382A) | C/T |
GALNT10 | rs2277937 | 5 | 153799165 | Mucin family | 3'-UTR | C/T |
MUC21 | rs1634730 | 6 | 30954245 | Mucin family | Missense (V98A) | C/T |
MUC12 | rs11766125 | 7 | 100648117 | Mucin family | Missense (T4758R) | C/G |
MUC17 | rs4729656 | 7 | 100701610 | Mucin family | 3'-UTR | A/T |
MUC15 | rs15783 | 11 | 26586801 | Mucin family | Missense (T229I) | A/G |
MUC15 | rs11029621 | 11 | 26596998 | Mucin family | 3' near gene | A/G |
MUC19 | rs2933353 | 12 | 40857943 | Mucin family | Missense (G1803A) | A/C |
GALNT4 | rs2230283 | 12 | 89916811 | Mucin family | Missense (V506I) | A/G |
GALNT1 | rs17647532 | 18 | 33234072 | Mucin family | Promoter | C/T |
MUC16 | rs1862458 | 19 | 9069792 | Mucin family | Missense (S5885F) | A/G |