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Figure 4 | BMC Cancer

Figure 4

From: A novel inhibitor of hypoxia-inducible factor-1α P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cells

Figure 4

P3155 downregulates HIF-1α expression as well as PI3K/Akt pathway under hypoxic conditions. (A) PC-3 cells were treated with given concentrations of P3155 under hypoxia and its effect on protein levels of HIF-1α, phospho-Akt, phospho-4E-BP1 and VEGF was determined using western blot analysis (B) densitometric analysis was carried out for each protein.

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