Serum estradiol levels associated with specific gene expression patterns in normal breast tissue and in breast carcinomas

Table 2 Genes independently associated with serum estradiol in a linear regression model.

Covariate	Estimate¹⁾	Std error	p-value
SCGB3A1	0.068	0.025	0.009
TLN2	0.142	0.061	0.024
PTGS1	-0.145	0.066	0.030
SLITRK4	0.086	0.075	0.25²⁾
RSPO1	0.045	0.045	0.32²⁾
DCLK1	0.023	0.063	0.71²⁾

All genes differentially expressed according to serum estradiol (Table 1) were included. Values shown are corrected for age, menopause and current hormone therapy. After leave-one-out stepwise selection the following covariates remained:
1) Estimate denotes the beta-value corresponding to each covariate in the regression equation.
2) Values for the non-significant genes are from the last model before they were excluded.

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