Figure 4From: Long-term exposure to hypoxia inhibits tumor progression of lung cancer in rats and mice Normoxia recovery and different levels of oxygen on lung cancer tumor growth in rats. Effect of normoxia recovery on hypoxia-induced reduction of lung cancer tumor growth (Figure 1E): (A) Tumor growth curve. Because large tumor mass was not allowed in living animals, we sacrificed the control rats when the tumor size reached over 1.5 cm. N = Rats under normoxia for entire experiment. H+N = Rats under hypoxia for 10 days and then under normoxia for another 8 days. Effect of different levels of oxygen on lung cancer tumor growth (Figure 1C) (B & C): (B) Tumor growth curve and (C) Tumor weight. n = 5 for each group. *p < 0.05 as compared with normoxia.Back to article page