Table 2 Sensitivity, specificity, PPV and NPV of serum S100B and PET-CT
From: Role of serum S100B and PET-CT in follow-up of patients with cutaneous melanoma
All pts (115) | ||||
|---|---|---|---|---|
| Â | PPV % (N) | NPV % (N) | Sensitivity % (N) | Specificity % (N) |
S100B | 81.0 (47/58) | 17.5 (10/57) | 50.0 (47/94) | 47.6 (10/21) |
PET-CT | 97.8 (93/95) | 95.0 (19/20) | 98.9 (93/94) | 90.4 (19/21) |
Pts with clin. sign (82) | ||||
| Â | PPV % (N) | NPV % (N) | Sensitivity % (N) | Specificity % (N) |
S100B | 96.0 (24/25) | 17.5 (10/57) | 33.8 (24/71) | 90.9 (10/11) |
PET-CT | 98.5 (70/71) | 90.9 (10/11) | 98.5 (70/71) | 90.9 (10/11) |
Asymptomatic pts (33) | ||||
| Â | PPV % (N) | NPV % (N) | Sensitivity % (N) | Specificity % (N) |
S100B | 69.7 (23/33) | 0 bias | 100.0 (23/23) | 0 bias |
PET-CT | 95.8 (23/24) | 100.0 (9/9) | 100.0 (23/23) | 90.0 (9/10) |