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Table 2 Sensitivity, specificity, PPV and NPV of serum S100B and PET-CT

From: Role of serum S100B and PET-CT in follow-up of patients with cutaneous melanoma

All pts
(115)
  PPV %
(N)
NPV %
(N)
Sensitivity % (N) Specificity % (N)
S100B 81.0 (47/58) 17.5 (10/57) 50.0 (47/94) 47.6 (10/21)
PET-CT 97.8 (93/95) 95.0 (19/20) 98.9 (93/94) 90.4 (19/21)
Pts with clin. sign
(82)
  PPV %
(N)
NPV %
(N)
Sensitivity % (N) Specificity % (N)
S100B 96.0 (24/25) 17.5 (10/57) 33.8 (24/71) 90.9 (10/11)
PET-CT 98.5 (70/71) 90.9 (10/11) 98.5 (70/71) 90.9 (10/11)
Asymptomatic pts
(33)
  PPV %
(N)
NPV %
(N)
Sensitivity % (N) Specificity % (N)
S100B 69.7 (23/33) 0 bias 100.0 (23/23) 0 bias
PET-CT 95.8 (23/24) 100.0 (9/9) 100.0 (23/23) 90.0 (9/10)