Table 5 Differentially expressed miRNAs between patients and healthy individuals: Testing against alternative that a miRNA is upregulated in patients

hsa-miR-296-5p

0.0049

MI0000747

chr 20: intronic (AL136532)

hsa-miR-766

0.0157

MI0003836

chr X: intronic ( SEPT6 )

+ (in families 1,15,232,362)

hsa-miR-767-3p

0.0189

MI0003763

chr X: intronic ( GABRA3 )

+ (in families

1, 15)

hsa-miR-151-5p

0.0312

MI0000809

chr 8: intronic ( PTK2 )

c.5-44T > C

c.*53C > T

+ (in family 1)

hsa-miR-133a

0.0316

133a-1: MI0000450

chr 18: intronic ( MIB1 )

c.74G > A

+ (in family 15)

133a-2: MI0000451

chr 20: intronic ( C20orf166 )

hsa-miR-451

0.0319

MI0001729

chr 17: intergenic

c.1327C > G

+ (in family 1)

hsa-miR-23b

0.0393

MI0000439

chr 9: intronic ( C9orf3 )

c.452C > T

c.1327C > G

+ (in families 1, 15, 413)

hsa-miR-223

0.0404

MI0000300

chr X: intergenic

+ (in families 1, 15, 362, 413)

hsa-miR-146a*

0.0404

MI0000477

chr 5: intergenic

hsa-miR-342-5p

0.0410

MI0000805

chr 14: intronic ( EVL )

c.452C > T

+ (in families 248, 292, 402, 408, 413)

hsa-miR-183*

0.0433

MI0000273

chr 7: intergenic

hsa-miR-151-3p

0.0438

MI0000809

chr 8: intronic ( PTK2 )

c.5-44T > C

c.*53C > T

+ (in families 1, 402)

hsa-miR-129-3p

0.0465

MI0000473

chr 11: intergenic

hsa-miR-129*

0.0477

MI0000252

chr 7: intergenic