Demographic variation in incidence of adult glioma by subtype, United States, 1992-2007

BMC Cancer

Table 4 Race/ethnic group-specific, period-adjusted Poisson regression coefficients (slopes) for the natural logarithm of age (log_e(age)) by glioma subtype, age 30 to 69 years, SEER, 1992-2007

Glioma		Male^a	Female^a	Total^b
Subtype	Race/ethnic group	Slope (log_e(age)) (95% CI^c)	Slope (log_e(age)) (95% CI^c)	Slope (log_e(age)) (95% CI^c)
GBM
	Total^d	4.12 (4.01, 4.23)	4.24 (4.10, 4.38)	4.17 (4.08, 4.26)
	Non-Hispanic White	4.09 (3.96, 4.21)	4.23 (4.07, 4.39)	4.14 (4.05, 4.24)
	Hispanic White	4.51 (4.17, 4.86)	4.39 (3.99, 4.78)	4.46 (4.20, 4.72)
	Black	4.29 (3.81, 4.76)	4.38 (3.83, 4.94)	4.33 (3.97, 4.69)
	Asian/Pacific Islander	3.70 (3.19, 4.21)	3.83 (3.19, 4.47)	3.75 (3.35, 4.15)
	American Indian/Alaskan Native	3.03 (1.28, 4.77)	4.39 (2.21, 6.56)	3.59 (2.23, 4.94)
	p-value for heterogeneity^e	0.044	0.68	0.021
Non-GBM
	Total^d	0.52 (0.40, 0.64)	0.43 (0.29, 0.56)	0.48 (0.39, 0.57)
	Non-Hispanic White	0.43 (0.29, 0.56)	0.38 (0.22, 0.54)	0.41 (0.30, 0.51)
	Hispanic White	1.13 (0.77, 1.49)	0.76 (0.38, 1.14)	0.95 (0.69, 1.21)
	Black	0.88 (0.34, 1.41)	0.68 (0.07, 1.29)	0.79 (0.39, 1.19)
	Asian/Pacific Islander	0.38 (-0.15, 0.91)	0.08 (-0.51, 0.66)	0.24 (-0.15, 0.63)
	American Indian/Alaskan Native	0.46 (-1.13, 2.05)	0.01 (-2.29, 1.61)	0.14 (-1.09, 1.38)
	p-value for heterogeneity^e	0.0053	0.22	0.0005

^aLog_e(age) coefficient adjusted for period by Poisson regression
^bLog_e(age) coefficient adjusted for period and sex by Poisson regression
^cConfidence interval
^dLog_e(age) coefficient additionally adjusted for race/ethnic group.
^eCalculated from the likelihood ratio test for the addition of the cross-product term for race/ethnic group by log_e(age) to the Poisson model

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