Well-differentiated leiomyosarcoma. A/H&E staining showing intersecting fascicles of moderately atypical elongated cells with abundant eosinophilic cytoplasm. Mitoses (black arrows) are seen (original magnification X 200). B-D/Immunohistochemical analysis showing that tumour cells strongly express smooth-muscle actin (B, X 200) and H-caldesmone (C, X 200). 15% of the cells are stained by Ki-67 proliferative marker (D, X 200).