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Table 5 Comparison of treatments and outcomes based on histologic subtypes

From: Multicenter retrospective analysis of 581 patients with primary intestinal non-hodgkin lymphoma from the Consortium for Improving Survival of Lymphoma (CISL)

Characteristics

DLBCL

No. (%)

MALT

No. (%)

BL

No. (%)

MCL

No. (%)

FL

No. (%)

PTCL-U

No. (%)

EATL

No. (%)

ENKTL

No. (%)

Treatment*

        

   Chemotherapy

368 (95.3)

30 (49.2)

29 (93.5)

19 (100.0)

5 (71.4)

30 (88.2)

23 (92.0)

17 (94.4)

   Surgical resection

223 (57.8)

25 (41.0)

9 (29.0)

1 (5.3)

3 (42.9)

9 (26.5)

12 (48.0)

7 (38.9)

   Radiotherapy

32 (8.3)

13 (21.3)

2 (6.5)

1 (5.3)

2 (28.6)

4 (11.8)

1 (4.0)

1 (5.6)

Response

        

   Complete response

264 (68.4)

36 (59.0)

22 (71.0)

11 (57.9)

4 (57.1)

11 (32.4)

7 (28.0)

5 (27.8)

   Partial response

36 (9.3)

5 (8.2)

5 (16.1)

5 (26.3)

0 (0.0)

4 (11.8)

4 (16.0)

3 (16.7)

Outcome

        

   Relapse or Progression

112 (29.0)

14 (23.0)

11 (35.5)

8 (42.1)

4 (57.1)

19 (55.9)

18 (72.0)

13 (73.2)

   Dead

87 (22.5)

8 (13.1)

7 (22.6)

6 (31.6)

2 (28.6)

18 (52.9)

15 (60.0)

9 (50.0)

Survival

        

   Median OS

Not reached

Not reached

Not reached

46 months

54 months

35 months

8.6 months

7 months

   5-year OS

72%

88%

76%

39%

42%

23%

35%

45%

   Median PFS

Not reached

115 months

Not reached

31 months

16 months

10 months

4.2 months

4 months

   5-year PFS

58%

80%

60%

0%

22%

17%

23%

21%

  1. *Some patients were treated with combined modality such as surgery plus chemotherapy. Thus, the sum of number of each treatment is larger than total number of patients.
  2. DLBCL: diffuse large B-cell lymphoma; MALT: extranodal marginal zone B-cell lymphoma; BL: Burkitt lymphoma; PTCL-U: peripheral T-cell lymphoma, unspecified; EATL: enteropathy-associated T-cell lymphoma; MCL: mantle cell lymphoma; ENKTL: extranodal natural killer/T-cell lymphoma; FL: follicular lymphoma