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Table 5 Event rates in patients with and without cancer

From: Heparin based prophylaxis to prevent venous thromboembolic events and death in patients with cancer - a subgroup analysis of CERTIFY

All patients

Pts with cancer at admission

Pts without cancer at admission

OR (95%CI)

p-value*

 

n/avail.

%

n/avail.

%

  

Thromboembolic events

      

   Combined endpoint

12/227

5.29

104/2516

4.13

1.29 (0.70-2.39)

0.4097

Proximal DVT

10/225

4.44

98/2516

3.90

1.15 (0.59-2.23)

0.6851

Symptomatic non-fatal PE

1/257

0.39

9/2827

0.32

1.22 (0.15-9.69)

0.8488

VTE related death

1/263

0.38

0/2852

0

-

-

   Distal DVT

17/207

8.21

178/2270

7.84

1.05 (0.63-1.77)

0.8495

   Proximal or distal DVT

21/207

10.14

218/2280

9.56

1.07 (0.67-1.71)

0.7851

   Symptomatic DVT

2/253

0.79

7/2814

0.25

3.20 (0.66-15.46)

0.1488

   Death from any cause

8/263

3.04

33/2852

1.16

2.68 (1.22-5.86)

0.0136

  1. Legend: Pts, patients; UFH, unfractionated heparin; DVT, deep venous thrombosis; PE, pulmonary embolism; OR, odds ratio; CI, confidence interval, * two-sided p-value for null-hypothesis: difference = 0 or odds ratio = 1.