Table 1 Baseline demographic characteristics for patients with or without cancer (safety population)
Pts with cancer at admission | Pts without cancer at admission | ||||
|---|---|---|---|---|---|
Certoparin (n = 133) | UFH (n = 141) | Total (n = 274) | Total (n = 2965) | p-value vs. pts with cancer | |
Female (%) | 37.6 | 40.4 | 39.1 | 61.0 | < 0.0001^ |
Mean age (± SD) (y) | 79.7 ± 6.4 | 78.3 ± 5.8 | 79.0 ± 6.1 | 78.8 ± 6.3 | 0.6922~ |
Mean bodyweight (± SD) (kg) | 73.4 ± 14.6 | 71.2 ± 13.7 | 72.3 ± 14.2 | 72.1 ± 15.9 | 0.8076~ |
Body Mass Index (± SD) (kg/m2) | 25.9 ± 4.5 | 25.4 ± 4.6 | 25.6 ± 4.6 | 26.6 ± 5.4 | 0.0041~ |
Reason for hospitalization (%) | |||||
Infections and infestations | 23.3 | 28.4 | 25.9 | 27.7 | 0.5210^ |
Cardiac disorders | 14.3 | 8.5 | 11.3 | 23.2 | < 0.0001^ |
Respiratory disease | 6.8 | 10.6 | 8.8 | 18.0 | < 0.0001^ |
Neurologic disease | 6.8 | 6.4 | 6.6 | 6.6 | 0.9791^ |
Gastrointestinal disease | 9.0 | 9.2 | 9.1 | 6.3 | 0.0753^ |
Vascular disease | 3.0 | 6.4 | 4.7 | 5.9 | 0.4454^ |
Renal status | |||||
GFR ≤ 30 ml/min/1.73 m2 | 4.6 | 2.9 | 3.7 | 6.1 | 0.1106* |
30 < GFR ≤ 60 ml/min/1.73 m2 | 52.7 | 50.0 | 51.3 | 52.2 | |
GFR > 60 ml/min/1.73 m2 | 42.7 | 47.1 | 45.0 | 41.6 | |
Antiplatelet use | |||||
Yes | 51.1 | 48.9 | 50.0 | 52.2 | 0.4905^ |
No | 48.9 | 51.1 | 50.0 | 47.8 | |
Hospitalization (mean ± SD) (days) | 13.0 ± 8.5 | 12.6 ± 5.2 | 12.8 ± 7.0 | 12.3 ± 6.0 | 0.2500~ |
Immobilization (mean ± SD) (days) | 10.7 ± 6.3 | 10.7 ± 4.5 | 10.7 ± 5.5 | 9.8 ± 4.2 | 0.0038~ |
Mean exposure (± SD) (days) | 9.2 ± 3.9 | 9.1 ± 4.0 | 9.2 ± 3.9 | 9.1 ± 3.3 | 0.6264~ |