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Table 1 IC50 values for E7080 in a panel of cell lines

From: E7080, a multi-targeted tyrosine kinase inhibitor suppresses tumor cell migration and invasion

Cell line

Origin

IC50(μM)a

95% Confidence interval

A375

Melanoma

44.17

37.24 - 51.09

DU145

Prostate cancer

23.62

20.02 - 27.20

DX3

Melanoma

33.95

21.11 - 46.79

KM12C

Colon cancer

9.54

7.94 - 11.14

SK23

Melanoma

42.57

40.19 - 44.94

U2OS

Osteosarcoma

34.82

31.36 - 38.28

  1. aMean values from at least 3 experiments