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Table 3 Cell cycle regulators are more affected by MT19C at earlier times while translation regulators and ribosomes are affected at later times by GSEA.

From: Integrated genomics of ovarian xenograft tumor progression and chemotherapy response

Geneset NES P-value FDR
Treat8 vs. Naive8    
Biocarta (n = 184)    
ATRBRCA pathway 1.74 0.000 0.315
MTA3 pathway -1.87 0.000 0.141
GenMapp (n = 107)    
DNA Replication 1.84 0.000 0.024
G1 to S Cell Cycle Reactome 1.59 0.006 0.122
Krebs TCA Cycle 1.49 0.033 0.219
Galactose metabolism -1.88 0.000 0.113
Oxidative Phosphorylation -1.68 0.002 0.139
Nuclear Receptors -1.59 0.013 0.227
Kegg (n = 165)    
Cell Cycle 1.94 0.000 0.013
Transcription factor targets (n = 614)    
E2F1s 1.76-2.05 0.000 0.000-0.008
Bach2 -1.73 0.000 0.037
Treat16 vs. Naive16    
Genmapp (n = 107)    
Ribosomal proteins 2.41 0.000 0.000
Aminoacyl tRNA biosynthesis 2.05 0.002 0.003
Translation Factors 1.66 0.005 0.203
  1. Comparisons are indicated byTreat8 vs. Naive8 and Treat16 vs. Naive 16. NES > 0 indicates higher expression in MT19C treated tumors and NES < 0 indicates higher expression in naïve tumors.