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Table 1 Gene Set Enrichment Analysis reveals MT19C down-regulation of energy metabolism and stimulation of DNA repair and apoptosis pathways.

From: Integrated genomics of ovarian xenograft tumor progression and chemotherapy response

Geneset NES P-value FDR GSEA
Kegg (n = 165)    
Cell Communication -1.97 0.000 0.029
Biosynthesis of Steroids -1.95 0.002 0.046
Galactose metabolism -1.84 0.005 0.082
Oxidative Phosphorylation -1.69 0.000 0.102
Notch signaling pathway -1.49 0.032 0.232
Ubiquitin mediated Proteolysis 1.98 0.000 0.021
Gene Ontology (n = 1307)    
Double Strand Break Repair 1.86 (1.85) 0.000 (0.006) 0.006
Ubiquitin Cycle 2.01 (1.96) 0.000 (0.000) 0.111
  1. NES > 1.4 indicates enriched in MT19C treated tumors compared to naïve tumors for all 8 and 16 day tumors, including T16C.