Skip to main content

Advertisement

Table 3 Univariate and multivariate analysis of predictors of bladder tumor relapse in 133 patients with TCC of the renal pelvis or ureter

From: Radiotherapy may improve overall survival of patients with T3/T4 transitional cell carcinoma of the renal pelvis or ureter and delay bladder tumour relapse

Variables n Bladder tumor relapse X2 p values
   Absent (n = 95) Present (n = 38)   univariate multivariate
Age       
   < 60 years 31 23(74.2%) 8(25.8%) 0.697 0.573 0.562
   ≥ 60 years 102 72(70.6%) 30(29.4%)    
Sex       
   Female 50 33(66.0%) 17(34.0%) 0.282 0.277 0.588
   Male 83 62(74.7%) 21(25.3%)    
Tumor location       
   Renal pelvis 42 36(85.7%) 6(14.3%) 0.013 0.048 0.015
   Ureter 91 59(64.8%) 32(35.2%)    
Tumor lesions       
   Solitary 117 83(70.9%) 34(29.1%) 0.736 0.628 0.352
   Multiple nodules 16 12(75.0%) 4(25.0%)    
pT classification       
   T1 or T2 81 59(72.8%) 22(27.2%) 0.653 0.255 0.256
   T3 or T4 52 36(69.2%) 16(30.8%)    
Synchronous LN       
   - 124 88(71.0%) 36(29.0%) 0.662 0.687 0.759
   + 9 7(77.8%) 2(22.2%)    
Resection models       
   Local resection 22 17(77.3%) 5(22.7%) 0.507 0.853 0.543
   Radical resection 111 78(70.3%) 33(29.7%)    
Residual Disease       
   R0 108 78(72.2%) 30(27.8%) 0.674 0.148 0.167
   R1 or R2 25 17(68.0%) 8(32.0%)    
Histological grade       
   Grade I or II 79 55(69.6%) 24(30.4%) 0.577 0.926 0.816
   Grade III or IV 54 40(74.1%) 14(25.9%)    
EBRT       
   Non-EBRT 66 43(65.2%) 23(34.8%) 0.112 0.060 0.514
   EBRT w/o bladder 67 52(77.6%) 15(22.4%)    
RT including bladder       
   No 80 49(61.3%) 31(38.7%) 0.001 0.002 < 0.001
   Yes 53 46(86.8%) 7(13.2%)    
  1. No lymph node metastasis was found in pT1 or T2 patients, so patients with T3 or T4 are equal to those with AJCC stage III or IV in this study. We did not use AJCC Stage III or IV in this table, because we excluded patients with distant metastases from our study, who are also regarded as stage IV.
  2. TCC: Transitional Cell arcinoma; LN: Lymph Node; EBRT: External Beam Radiation Therapy