Table 3 Comparison of IC50 values obtained for C7a and cisplatin
IC 50 Complex 7a (μM) | IC 50 Cisplatin (μM) | |
|---|---|---|
Murine Melanoma | ||
B16F10-Nex2 Human tumor lineages | 0.42 ± 0.06 | 176 ± 15 |
Colon Cancer | ||
LS-180 | 0.26 ± 0.07 | >200 |
HCT-8 | 0.34 ± 0.05 | >200 |
Breast Cancer | ||
SKBr-3 | 0.26 ± 0.04 | 66 ± 7 |
ZR753A | 0.34 ± 0.02 | >200 |
Uterine Cervix Cancer | ||
HeLa | 0.30 ± 0.03 | 68 ± 4 |
CasKi | 0.24 ± 0.01 | 140 ± 8 |
SiHa | 0.19 ± 0.02 | >200 |
Melanoma | ||
Me91 | 0.14 ± 0.03 | 156 ± 8 |
SK-Mel 25 | 0.15 ± 0.01 | >200 |
Leukemia | ||
HL-60 | 1.0 ± 0.1 | 70 ± 5 |
Glioblastoma | ||
U-87 | 3.5 ± 0.2 | 150 ± 20 |