Skip to main content

Table 3 Polymorphism distribution

From: Dose and polymorphic genes xrcc1, xrcc3, gst play a role in the risk of developing erythema in breast cancer patients following single shot partial breast irradiation after conservative surgery

Gene SNPs ds SNP ID Observed Genotype
(n. Pts)
allele frequencies(%) %CEU
    AA Aa aa allele A allele
a
allele A allele a
XRCC3 A4541G (rs1799794) 32 23 2 78% 22% 74% 26%
XRCC3 Thr241Met (rs861539) 18 33 6 61% 39% 61% 39%
XRCC1 Arg399Gln (rs25487) 31 23 3 75% 25% 57% 43%
GSTP1 Ile105Val (rs1695) 32 22 3 75% 24% 65% 35%
RAD51 G135C (rs1801320) 54 3 / 96% 4% 97% 3%
GSTA1 G > A (rs3957356) 12 35 10 53% 47% 61% 32%
XRCC1 Arg194Trp (rs1799782) 44 12 1 88% 12% 76% 24%
  1. Abbreviations: %CEU = frequencies in European population.