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Table 3 Relationship between mutagen sensitivity and polymorphisms in BRCA1 185delAG and 5382insC mutations carriers who are unrelated

From: Association of Rad51 polymorphism with DNA repair in BRCA1 mutation carriers and sporadic breast cancer risk

   Genotype Low   High   Fisher's p
185delAG    n = 8 % n = 17 %  
  E1038G TT 0 0 0 0  
   CT 3 20.0% 8 53.3%  
   CC 3 20.0% 2 13.3% 0.25
  D693N CC 4 28.6% 8 57.1%  
   CT 0 0.0% 2 14.3% >0.99
  Q356R TT 5 17.9% 7 25.0%  
   CT 1 3.6% 1 3.6% 0.45
  Rad51 GG 8 32.0% 10 40.0%  
   CG/CC 0 0.0% 7 28.0% 0.06
    Low   High   Fisher's p
5382insC    n = 3 % n = 8 %  
  E1038G TT 2 28.6% 3 42.9%  
   CT/CC 0 0.0% 2 28.6% >0.99
  D693N CC 2 28.6% 4 57.1%  
   CT 0 0.0% 1 14.3% 0.73