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Table 1 Demographics of high-risk breast cancer subjects

From: Association of Rad51 polymorphism with DNA repair in BRCA1 mutation carriers and sporadic breast cancer risk

  Unaffected Affected p-value
  N = 56 N = 82  
Age at Diagnosis Range (yrs) 25-78 27-79  
Mean Age at Diagnosis (yrs) 47.44 44.73 0.19*
Median Age at Diagnosis (yrs) 50 45  
Standard Deviation 13.63 10.65  
Mutation    
185delAG (BRCA1) 19 (31.6%) 21 (24.7%)  
5382insC 4 (7.0%) 12 (14.8%) 0.15**
Other 35 (61.4%) 49 (60.5%) 0.57**
  Relationship Information   
   Num. Pairs  
Sister-Sister   15  
Other relationship    
i.e. Aunt-Niece and Cousins   16  
  1. *Unpaired t-test, t = 1.13, df = 136
  2. **Determined by Fisher's exact test.