Skip to main content
Figure 3 | BMC Cancer

Figure 3

From: Altered efficacy of AT1R-targeted treatment after spontaneous cancer cell-AT1R upregulation

Figure 3

Intensity of AT1R staining 21 days after tumour inoculation in untreated (control) animals with tumours showing sensitivity to irbesartan or insensitive to irbesartan treatment. Tumours were grouped into small (≤ 250 μm), medium (250 μm to 1000 μm), or large (≥ 1000 μm) in diameter. Representative images are shown below. n = 5 or 6 for each group except for AT1RLOW tumours which, because of the reduced tumour load, had additional samples (n of 10). The entire tumour was imaged for analysis. Significant P values between 0.01 and 0.05 are shown with an *, those less than 0.01 are shown with **. Data are presented as mean ± S.E.M.

Back to article page