Figure 1
From: Altered efficacy of AT1R-targeted treatment after spontaneous cancer cell-AT1R upregulation
Liver to body weight ratio 21 days after tumour inoculation with continuous RAS-targeted single treatments (A). Percent liver metastases for irbesartan and ANG-(1-7) or control (untreated) animals from the same study as above (B). Telmisartan and irbesartan are AT1R blockers, while captopril is an ANCE inhibitor. n = 5 or 6 for each group. Significant P values between 0.01 and 0.05 are shown with an *, those less than 0.01 are shown with **. Data are presented as mean ± S.E.M.