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Figure 1 | BMC Cancer

Figure 1

From: Combined mRNA expression levels of members of the urokinase plasminogen activator (uPA) system correlate with disease-associated survival of soft-tissue sarcoma patients

Figure 1

Multivariate Cox regression analysis for the association of combined PAI-1/uPAR-del4/5 mRNA values with disease-associated survival in the subgroup of STS patients with complete tumor resection (R0). For each, the PAI-1 and the uPAR-del4/5 mRNA level, the 33% percentile of the relative expression ratio was used as cut-off point. Group 1 (n = 13), low expression levels of PAI-1/uPAR-del4/5 mRNA; group 2 (n = 8), one of the mRNA values was either low or high; group 3 (n = 30), high expression levels of PAI-1/uPAR-del4/5 mRNA. R0 patients of group 3 (high expression of PAI-1/uPAR-del4/5 mRNA) showed a 19-fold increased risk of tumor-related death (RR = 19.1, 95%CI = 1.1-335.3, P = 0.044) compared to group 1 with low expression of PAI-1/uPAR-del4/5 mRNA.

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BMC Cancer

ISSN: 1471-2407

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