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Table 3 Correlations between the MVA and pFOXO1 expression in tumor cells in HIF-1α-positive and HIF-1α-negative tumors and in VEGF-positive and VEGF-negative tumors

From: Constitutive phosphorylation of the FOXO1 transcription factor in gastric cancer cells correlates with microvessel area and the expressions of angiogenesis-related molecules

 

MVA

 
 

Cases

Mean ± S.D.

P

HIF-1 positive

   

   pFOXO1

   

Positive

61

12.06 ± 10.9

0.336

Negative

3

5.85 ± 9.0

 

HIF-1 negative

   

   pFOXO1

   

Positive

130

9.40 ± 7.2

0.332

Negative

33

8.11 ± 5.2

 

VEGF positive

   

   pFOXO1

   

Positive

84

10.49 ± 8.2

0.667

Negative

6

9.02 ± 4.3

 

VEGF negative

   

   pFOXO1

   

Positive

107

10.79 ± 9.3

0.071

Negative

30

7.56 ± 5.5

 
  1. Abbreviations: pFOXO1, phosphorylated Forkhead in rhabdomyosarcoma (cytoplasmic staining); HIF-1α, hypoxia inducible factor-1α (nuclear staining); VEGF, vessel endothelial growth factor (cytoplasmic staining)
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BMC Cancer

ISSN: 1471-2407

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