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Figure 4 | BMC Cancer

Figure 4

From: Expression of Tissue factor in Adenocarcinoma and Squamous Cell Carcinoma of the Uterine Cervix: Implications for immunotherapy with hI-con1, a factor VII-IgGFcchimeric protein targeting tissue factor

Figure 4

Representative effect of low doses of interleukin-2 (IL-2) in combination with hI-con1 (30 μg/ml) on ADCC against CVX-2 ARK-2 primary cell line (Effectors to target ratio 50:1 and 25: 1). PBL from healthy donors were incubated for 5 hours in the presence of 100 IU/ml of IL-2. hI-con1-DCC was significantly increased in the presence of low doses of IL-2. No significant increase in cytotoxicity was detected after 5-h IL-2 treatment in the absence of hI-con1 or in the presence of the rituximab isotype control mAb.

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