Figure 4

Human immunoglobulin light chain protein levels in the sera of mice after treated with three sorts of MM cells. There were significant differences in the human immunoglobulin light chain protein levels in the sera of the mice in the three groups treated with three sorts of MM cells (all P < 0.01). (A) Light chain levels of SCID-rab MM mice with tumors derived from U266 cells at 16 weeks [PF4 (346.3 ± 45.4 pg/ml); p17-70 (327.8 ± 34.2 pg/ml); U266-neo (823.2 ± 53.7 pg/ml)]. (B) Light chain levels of SCID-rab MM mice with tumors derived from RPMI8226 cells at 16 weeks [RPMI8226: PF4 (325.6 ± 47.3 pg/ml); p17-70 gene fragment (338.0 ± 36.1 pg/ml); RPMI8226-neo (778.7 ± 55.1)]. (C) Light chain levels of SCID-rab MM mice with tumors derived from LP-1 cells at 16 weeks [PF4 (334.6 ± 53.1 pg/ml); p17-70 (289.0 ± 32.7 pg/ml); LP-1-neo (819.7 ± 56.3 pg/ml)].